Solid-phase synthesis of an RNA nucleopeptide fragment from the nucleoprotein of poliovirus.

The naturally occurring RNA-nucleopeptide H-Ala-Tyr[5'-pUUAAAAC-3']-NH2 is prepared via a solid-phase phosphite triester approach using N-SiOMB/O-TBDMS-protected nucleosides. Preliminary 1H-NMR studies show that the peptidyl unit has a remarkable effect on the conformational behaviour of t...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Dreef-Tromp, C M, van den Elst, H, van den Boogaart, J E, van der Marel, G A, van Boom, J H
Format: Artigo
Language:Inglês
Published: Oxford University Press 1992
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1317954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.10.2435
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