Peroxisome Proliferator Activated Receptor-α Agonist Slows the Progression of Hypertension, Attenuates Plasma Interleukin-6 Levels and Renal Inflammatory Markers in Angiotensin II Infused Mice

The anti-inflammatory properties of PPAR-α plays an important role in attenuating hypertension. The current study determines the anti-hypertensive and anti-inflammatory role of PPAR-α agonist during a slow-pressor dose of Ang II (400 ng/kg/min). Ten to twelve week old male PPAR-α KO mice and their W...

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Autores principales: Wilson, Justin L., Duan, Rong, El-Marakby, Ahmed, Alhashim, Abdulmohsin, Lee, Dexter L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405818/
https://ncbi.nlm.nih.gov/pubmed/22848208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/645969
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