The environmental stressor ultraviolet B radiation inhibits murine antitumor immunity through its ability to generate platelet-activating factor agonists

Ubiquitous pro-oxidative stressor ultraviolet B radiation (UVB) to human or mouse skin generates platelet-activating factor (PAF) and novel oxidatively modified glycerophosphocholines (Ox-GPCs) with PAF-receptor (PAF-R) agonistic activity. These lipids mediate systemic immunosuppression in a process...

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Autori principali: Sahu, Ravi P., Turner, Matthew J., DaSilva, Sonia C., Rashid, Badri M., Ocana, Jesus A., Perkins, Susan M., Konger, Raymond L., Touloukian, Christopher E., Kaplan, Mark H., Travers, Jeffrey B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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None
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405652/
https://ncbi.nlm.nih.gov/pubmed/22542595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs152
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