Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer

Four loci have been associated with pancreatic cancer through genome-wide association studies (GWAS). Pathway-based analysis of GWAS data is a complementary approach to identify groups of genes or biological pathways enriched with disease-associated single-nucleotide polymorphisms (SNPs) whose indiv...

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Main Authors: Li, Donghui, Duell, Eric J., Yu, Kai, Risch, Harvey A., Olson, Sara H., Kooperberg, Charles, Wolpin, Brian M., Jiao, Li, Dong, Xiaoqun, Wheeler, Bill, Arslan, Alan A., Bueno-de-Mesquita, H. Bas, Fuchs, Charles S., Gallinger, Steven, Gross, Myron, Hartge, Patricia, Hoover, Robert N., Holly, Elizabeth A., Jacobs, Eric J., Klein, Alison P., LaCroix, Andrea, Mandelson, Margaret T., Petersen, Gloria, Zheng, Wei, Agalliu, Ilir, Albanes, Demetrius, Boutron-Ruault, Marie-Christine, Bracci, Paige M., Buring, Julie E., Canzian, Federico, Chang, Kenneth, Chanock, Stephen J., Cotterchio, Michelle, Gaziano, J.Michael, Giovannucci, Edward L., Goggins, Michael, Hallmans, Göran, Hankinson, Susan E., Hoffman Bolton, Judith A., Hunter, David J., Hutchinson, Amy, Jacobs, Kevin B., Jenab, Mazda, Khaw, Kay-Tee, Kraft, Peter, Krogh, Vittorio, Kurtz, Robert C., McWilliams, Robert R., Mendelsohn, Julie B., Patel, Alpa V., Rabe, Kari G., Riboli, Elio, Shu, Xiao-Ou, Tjønneland, Anne, Tobias, Geoffrey S., Trichopoulos, Dimitrios, Virtamo, Jarmo, Visvanathan, Kala, Watters, Joanne, Yu, Herbert, Zeleniuch-Jacquotte, Anne, Amundadottir, Laufey, Stolzenberg-Solomon, Rachael Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
None
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405651/
https://ncbi.nlm.nih.gov/pubmed/22523087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs151
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