Recovery of Influenza B Virus with the H273Y Point Mutation in the Neuraminidase Active Site from a Human Patient

The H275Y oseltamivir resistance mutation confers high-level resistance to oseltamivir in isolates of human A(H1N1) influenza. We report the recovery and identification of an influenza B virus with the H273Y neuraminidase point mutation directly from a human patient. The H273Y influenza B isolate is...

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Hlavní autoři: Higgins, Rachel R., Beniprashad, Melissa, Chong-King, Eddie, Li, Yan, Bastien, Nathalie, Low, Donald E., Gubbay, Jonathan B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Virology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405592/
https://ncbi.nlm.nih.gov/pubmed/22535992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00682-12
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