Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010–2011 influenza season: high prevalence of mutations at antigenic sites

BACKGROUND: The direct effect of antigenic site mutations in influenza viruses on antigenic drift and vaccine effectiveness is poorly understood. OBJECTIVE: To investigate the genetic and antigenic characteristics of human influenza A (H3N2) viruses circulating in Ontario during the early 2010–2011...

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Main Authors: Eshaghi, AliReza, Duvvuri, Venkata R, Li, Aimin, Patel, Samir N, Bastien, Nathalie, Li, Yan, Low, Donald E, Gubbay, Jonathan B
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2014
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186474/
https://ncbi.nlm.nih.gov/pubmed/24313991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12219
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