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Assembly of pre-mRNA splicing complex is cap dependent.

To study the influence of the ubiquitous cap structure of nuclear pre-mRNAs on the assembly of a functional splicing complex, the in vitro splicing of a truncated human metallothionein pre-mRNA was examined in the presence of the cap analogue m7GTP. Significant inhibition of splicing was observed at...

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Autori principali: Patzelt, E, Thalmann, E, Hartmuth, K, Blaas, D, Kuechler, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1987
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC340556/
https://ncbi.nlm.nih.gov/pubmed/3644239
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