Inhibition of hepatic scavenger receptor-class B type I by RNA interference decreases atherosclerosis in rabbits

OBJECTIVE: Scavenger receptor-class B type I (SR-BI), the receptor for HDL-cholesterol, plays a key role in HDL metabolism, whole body cholesterol homeostasis, and reverse cholesterol transport. We investigated the in vivo impact of hepatic SR-BI inhibition on lipoprotein metabolism and the developm...

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Detalhes bibliográficos
Main Authors: Demetz, Egon, Tancevski, Ivan, Duwensee, Kristina, Stanzl, Ursula, Huber, Eva, Heim, Christiane, Handle, Florian, Theurl, Markus, Schroll, Andrea, Tailleux, Anne, Dietrich, Hermann, Patsch, Josef R., Eller, Philipp, Ritsch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405511/
https://ncbi.nlm.nih.gov/pubmed/22494625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.03.012
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