Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

Comparison of transcriptomic and proteomic data from pathologically similar multiple sclerosis (MS) lesions reveals down-regulation of CD47 at the messenger RNA level and low abundance at the protein level. Immunohistochemical studies demonstrate that CD47 is expressed in normal myelin and in foamy...

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Hauptverfasser: Han, May H., Lundgren, Deborah H., Jaiswal, Siddhartha, Chao, Mark, Graham, Kareem L., Garris, Christopher S., Axtell, Robert C., Ho, Peggy P., Lock, Christopher B., Woodard, Joslyn I., Brownell, Sara E., Zoudilova, Maria, Hunt, Jack F.V., Baranzini, Sergio E., Butcher, Eugene C., Raine, Cedric S., Sobel, Raymond A., Han, David K., Weissman, Irving, Steinman, Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405500/
https://ncbi.nlm.nih.gov/pubmed/22734047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20101974
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