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The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications.

A simple, effective measure of synonymous codon usage bias, the Codon Adaptation Index, is detailed. The index uses a reference set of highly expressed genes from a species to assess the relative merits of each codon, and a score for a gene is calculated from the frequency of use of all codons in th...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Sharp, P M, Li, W H
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1987
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3547335/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.3.1281
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