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The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications.

A simple, effective measure of synonymous codon usage bias, the Codon Adaptation Index, is detailed. The index uses a reference set of highly expressed genes from a species to assess the relative merits of each codon, and a score for a gene is calculated from the frequency of use of all codons in th...

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Détails bibliographiques
Auteurs principaux: Sharp, P M, Li, W H
Format: Artigo
Langue:Inglês
Publié: 1987
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC340524/
https://ncbi.nlm.nih.gov/pubmed/3547335
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