PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

BACKGROUND: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases in diffuse large B-cell lymphoma (DLBCL) biopsy samples and DLBCL cell lines....

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Detalhes bibliográficos
Main Authors: Brault, L, Menter, T, Obermann, E C, Knapp, S, Thommen, S, Schwaller, J, Tzankov, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405213/
https://ncbi.nlm.nih.gov/pubmed/22722314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.272
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