PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

BACKGROUND: PIM serine/threonine kinases are often highly expressed in haematological malignancies. We have shown that PIM inhibitors reduced the survival and migration of leukaemic cells. Here, we investigated PIM kinases in diffuse large B-cell lymphoma (DLBCL) biopsy samples and DLBCL cell lines....

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Hlavní autoři: Brault, L, Menter, T, Obermann, E C, Knapp, S, Thommen, S, Schwaller, J, Tzankov, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
Molecular Diagnostics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405213/
https://ncbi.nlm.nih.gov/pubmed/22722314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.272
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