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Discovery of novel sulfonated small molecules that inhibit vascular tube formation

Tumor-associated angiogenesis is a complex process that involves the interplay among several molecular players such as cell-surface heparan sulfate proteoglycans, vascular endothelial growth factors and their cognate receptors. PI-88, a highly sulfonated oligosaccharide, has been shown to have poten...

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Detalhes bibliográficos
Main Authors: Raman, Karthik, Karuturi, Rajesh, Swarup, Vimal P., Desai, Umesh R., Kuberan, Balagurunathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405149/
https://ncbi.nlm.nih.gov/pubmed/22627041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.04.014
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