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Neurogranin Targets Calmodulin and Lowers the Threshold for the Induction of Long-Term Potentiation

Calcium entry and the subsequent activation of CaMKII trigger synaptic plasticity in many brain regions. The induction of long-term potentiation (LTP) in the CA1 region of the hippocampus requires a relatively high amount of calcium-calmodulin. This requirement is usually explained, based on in vitr...

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Autors principals: Zhong, Ling, Gerges, Nashaat Z.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405117/
https://ncbi.nlm.nih.gov/pubmed/22848456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041275
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