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Neurogranin Targets Calmodulin and Lowers the Threshold for the Induction of Long-Term Potentiation
Calcium entry and the subsequent activation of CaMKII trigger synaptic plasticity in many brain regions. The induction of long-term potentiation (LTP) in the CA1 region of the hippocampus requires a relatively high amount of calcium-calmodulin. This requirement is usually explained, based on in vitr...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3405117/ https://ncbi.nlm.nih.gov/pubmed/22848456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041275 |
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