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A monoclonal antibody to triplex DNA binds to eucaryotic chromosomes.

A monoclonal antibody (Jel 318) was produced by immunizing mice with poly[d(TmC)].poly[d(GA)].poly[d(mCT) which forms a stable triplex at neutral pH. Jel 318 did not bind to calf thymus DNA or other non pyrimidine.purine DNAs such as poly[d(TG)].poly[d(CA)]. In addition the antibody did not recogniz...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, J S, Burkholder, G D, Latimer, L J, Haug, B L, Braun, R P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC340507/
https://ncbi.nlm.nih.gov/pubmed/2434928
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