A monoclonal antibody to triplex DNA binds to eucaryotic chromosomes.

A monoclonal antibody (Jel 318) was produced by immunizing mice with poly[d(TmC)].poly[d(GA)].poly[d(mCT) which forms a stable triplex at neutral pH. Jel 318 did not bind to calf thymus DNA or other non pyrimidine.purine DNAs such as poly[d(TG)].poly[d(CA)]. In addition the antibody did not recogniz...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Lee, J S, Burkholder, G D, Latimer, L J, Haug, B L, Braun, R P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1987
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2434928/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.3.1047
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