Dexamethasone blocks the systemic inflammation of alveolar hypoxia at several sites in the inflammatory cascade

Alveolar hypoxia produces a rapid and widespread systemic inflammation in rats. The inflammation is initiated by the release into the circulation of monocyte chemoattractant protein-1 (MCP-1) from alveolar macrophages (AMO) activated by the low alveolar Po(2). Circulating MCP-1 induces mast cell (MC...

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Detalhes bibliográficos
Main Authors: Chao, Jie, Viets, Zachary, Donham, Paula, Wood, John G., Gonzalez, Norberto C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404698/
https://ncbi.nlm.nih.gov/pubmed/22610172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00106.2012
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