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Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia

Reduced alveolar Po(2) in rats produces a rapid systemic inflammation characterized by reactive O(2) species generation, mast cell (MC) degranulation, leukocyte-endothelial interactions, and increased vascular permeability. The inflammation is not initiated by the low systemic Po(2) but rather by th...

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Detalhes bibliográficos
Main Authors: Chao, Jie, Blanco, Gustavo, Wood, John G., Gonzalez, Norberto C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233815/
https://ncbi.nlm.nih.gov/pubmed/21963836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00461.2011
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