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A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model

Preeclampsia is defined as new-onset hypertension with proteinuria after 20 wk gestation and is hypothesized to be due to shallow trophoblast invasion in the spiral arteries thus resulting in progressive placental ischemia as the fetus grows. Many animal models have been developed that mimic changes...

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Autori principali: Li, Jing, LaMarca, Babbette, Reckelhoff, Jane F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404644/
https://ncbi.nlm.nih.gov/pubmed/22523250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00117.2012
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