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A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model

Preeclampsia is defined as new-onset hypertension with proteinuria after 20 wk gestation and is hypothesized to be due to shallow trophoblast invasion in the spiral arteries thus resulting in progressive placental ischemia as the fetus grows. Many animal models have been developed that mimic changes...

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Detalhes bibliográficos
Main Authors: Li, Jing, LaMarca, Babbette, Reckelhoff, Jane F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404644/
https://ncbi.nlm.nih.gov/pubmed/22523250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00117.2012
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