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Cell cycle regulated synthesis of stable mouse thymidine kinase mRNA is mediated by a sequence within the cDNA.

The cDNA for mouse thymidine kinase (TK) was isolated from a cDNA library in lambda-gt11 and sequenced. It was used as a probe to follow the time course of TK mRNA expression in growth stimulated mouse fibroblasts. Linked to the HSV-TK promoter the cDNA was able to transform LTK-cells to the TK+ phe...

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Autores principales: Hofbauer, R, Müllner, E, Seiser, C, Wintersberger, E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC340464/
https://ncbi.nlm.nih.gov/pubmed/3822814
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