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Multiple exposures to unloading decrease bone's responsivity but compound skeletal losses in C57BL/6 mice

A single exposure to mechanical unloading can result in significant bone loss, but the consequences of multiple exposures are largely unknown. Within a 18-wk period, adult C57BL/6 male mice were exposed to 2 wk of hindlimb unloading (HLU) followed by 4 wk of reambulation (RA) once (1x-HLU), twice (2...

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Autors principals: Gupta, Shikha, Vijayaraghavan, Surabhi, Uzer, Gunes, Judex, Stefan
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404633/
https://ncbi.nlm.nih.gov/pubmed/22592559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00499.2011
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