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Acid contact in the rodent pulmonary alveolus causes proinflammatory signaling by membrane pore formation

Although gastric acid aspiration causes rapid lung inflammation and acute lung injury, the initiating mechanisms are not known. To determine alveolar epithelial responses to acid, we viewed live alveoli of the isolated lung by fluorescence microscopy, then we microinjected the alveoli with HCl at pH...

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Detalhes bibliográficos
Main Authors: Westphalen, Kristin, Monma, Eiji, Islam, Mohammad N., Bhattacharya, Jahar
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404630/
https://ncbi.nlm.nih.gov/pubmed/22561462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00206.2011
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