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Multiple ligand-specific conformations of the β(2)-adrenergic receptor
Seven-transmembrane receptors (7TMRs), also called G protein–coupled receptors (GPCRs), represent the largest class of drug targets, and they can signal through several distinct mechanisms including those mediated by G proteins and the multifunctional adaptor proteins β-arrestins. Moreover, several...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404607/ https://ncbi.nlm.nih.gov/pubmed/21857662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.634 |
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