Plasmacytoid Dendritic Cells Promote Host Defense Against Acute Pneumovirus Infection via the TLR7-MyD88-Dependent Signaling Pathway

Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in infants. In human infants, plasmacytoid dendritic cells (pDC) are recruited to the nasal compartment during infection and initiate host defense through the secretion of type I IFN, IL-12 and IL-6. Ho...

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Bibliografiska uppgifter
Huvudupphovsmän: Davidson, Sophia, Kaiko, Gerard, Loh, Zhixuan, Lalwani, Amit, Zhang, Vivian, Spann, Kirsten, Foo, Shen Yun, Hansbro, Nicole, Uematsu, Satoshi, Akira, Shizuo, Matthaei, Klaus I., Rosenberg, Helene F., Foster, Paul S., Phipps, Simon
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404606/
https://ncbi.nlm.nih.gov/pubmed/21482736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002635
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