Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model

AIMS: Remodelling of the extracellular matrix (ECM) plays an important role in the production of arrhythmogenic substrate for atrial fibrillation (AF), and is considered to be promoted by the connective tissue growth factor (CTGF). Our objective was to assess the relationship between CTGF and ECM sy...

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Bibliografiset tiedot
Päätekijät: Kiryu, Michiro, Niwano, Shinichi, Niwano, Hiroe, Kishihara, Jun, Aoyama, Yuya, Fukaya, Hidehira, Masaki, Yoshihiko, Izumi, Tohru
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2012
Aiheet:
Basic Science
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404558/
https://ncbi.nlm.nih.gov/pubmed/22454409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/europace/eus052
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