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Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model

AIMS: Remodelling of the extracellular matrix (ECM) plays an important role in the production of arrhythmogenic substrate for atrial fibrillation (AF), and is considered to be promoted by the connective tissue growth factor (CTGF). Our objective was to assess the relationship between CTGF and ECM sy...

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Bibliografske podrobnosti
Main Authors: Kiryu, Michiro, Niwano, Shinichi, Niwano, Hiroe, Kishihara, Jun, Aoyama, Yuya, Fukaya, Hidehira, Masaki, Yoshihiko, Izumi, Tohru
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404558/
https://ncbi.nlm.nih.gov/pubmed/22454409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/europace/eus052
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