Plasmid mediated mutagenesis of a cellular gene in transfected eukaryotic cells.

NIH3T3 cells are widely used in transformation assays and readily take up transfected DNA. A system has been devised using NIH3T3 cells to measure the mutagenic effect of transfected DNA on recipient cell genes. NIH3T3 cells can be mutated to 6-thioguanine resistance at a frequency which suggests th...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Brandt, C R, Buonaguro, F M, McDougall, J K, Galloway, D A
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1987
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.2.561
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