Plasmid mediated mutagenesis of a cellular gene in transfected eukaryotic cells.
NIH3T3 cells are widely used in transformation assays and readily take up transfected DNA. A system has been devised using NIH3T3 cells to measure the mutagenic effect of transfected DNA on recipient cell genes. NIH3T3 cells can be mutated to 6-thioguanine resistance at a frequency which suggests th...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1987
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340452/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3469621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.2.561 |
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