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cAMP stimulation of STAR expression and cholesterol metabolism is modulated by co-expression of labile suppressors of transcription and mRNA turnover
The steroidogenic acute regulatory protein (StAR) is generated in rodents from 1.6kb and 3.5kb mRNA formed by alternative polyadenylation. The zinc finger protein, TIS11B (also Znf36L1), is elevated by cAMP in adrenal cells in parallel with StAR mRNA. TIS11b selectively destabilizes the 3.5kb mRNA t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404512/ https://ncbi.nlm.nih.gov/pubmed/21147196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.12.006 |
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