Tailoring subunit vaccine immunogenicity: Maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1()

Subunit vaccination modalities tend to induce particular immune effector responses. Viral vectors are well known for their ability to induce strong T cell responses, while protein-adjuvant vaccines have been used primarily for induction of antibody responses. Here, we demonstrate in mice using a Pla...

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Main Authors: Douglas, Alexander D., de Cassan, Simone C., Dicks, Matthew D.J., Gilbert, Sarah C., Hill, Adrian V.S., Draper, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404461/
https://ncbi.nlm.nih.gov/pubmed/20937436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.08.068
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