Rapid measurement of 8-oxo-7,8-dihydro-2′-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography–tandem mass spectrometry

Interaction of reactive oxygen species with DNA results in a variety of modifications, including 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), which has been extensively studied as a biomarker of oxidative stress. Oxidative stress is implicated in a number of pathophysiological processes relevant t...

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Main Authors: Lam, Patricia M.W., Mistry, Vilas, Marczylo, Timothy H., Konje, Justin C., Evans, Mark D., Cooke, Marcus S.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Science 2012
Teme:
Original Contribution
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404459/
https://ncbi.nlm.nih.gov/pubmed/22542794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.03.004
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