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CAV1 siRNA Reduces Membrane Estrogen Receptor-α Levels and Attenuates Sexual Receptivity

Although classic estrogen receptors (ER) have been proposed to mediate estradiol signaling, it has been relatively recently that mechanisms of trafficking these receptors have been elucidated. ERα is palmitoylated and associates with caveolin proteins to be targeted to the cell membrane. Caveolins a...

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Détails bibliographiques
Auteurs principaux: Christensen, Amy, Micevych, Paul
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404361/
https://ncbi.nlm.nih.gov/pubmed/22669893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1312
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