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CAV1 siRNA Reduces Membrane Estrogen Receptor-α Levels and Attenuates Sexual Receptivity

Although classic estrogen receptors (ER) have been proposed to mediate estradiol signaling, it has been relatively recently that mechanisms of trafficking these receptors have been elucidated. ERα is palmitoylated and associates with caveolin proteins to be targeted to the cell membrane. Caveolins a...

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Detalhes bibliográficos
Main Authors: Christensen, Amy, Micevych, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404361/
https://ncbi.nlm.nih.gov/pubmed/22669893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1312
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