TNFR1-Activated Reactive Oxidative Species Signals Up-Regulate Osteogenic Msx2 Programs in Aortic Myofibroblasts

In LDLR(−/−) mice fed high-fat diabetogenic diets, osteogenic gene-regulatory programs are ectopically activated in vascular myofibroblasts and smooth muscle cells that promote arteriosclerotic calcium deposition. Msx2-Wnt signaling pathways previously identified as important for craniofacial skelet...

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Главные авторы: Lai, Chung-Fang, Shao, Jian-Su, Behrmann, Abraham, Krchma, Karen, Cheng, Su-Li, Towler, Dwight A.
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2012
Предметы:
Renal-Cardiac-Vascular
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404358/
https://ncbi.nlm.nih.gov/pubmed/22685265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1216
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