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Dkk1 and Msx2-Wnt7b Signaling Reciprocally Regulate The Endothelial-Mesenchymal Transition In Aortic Endothelial Cells
OBJECTIVE: Endothelial cells (ECs) can undergo an endothelial-mesenchymal transition (EndMT) with tissue fibrosis. Wnt- and Msx2-regulated signals participate in arteriosclerotic fibrosis and calcification. We studied the impact of Wnt7, Msx2, and Dkk1 – a Wnt7 antagonist -- on EndMT in primary aort...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837473/ https://ncbi.nlm.nih.gov/pubmed/23685555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.300647 |
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