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Insertion-Deletions In a FADS2 Intron 1 Conserved Regulatory Locus Control Expression Of Fatty Acid Desaturases 1 and 2 And Modulate Response To Simvastatin

The fatty acid desaturase genes (FADS1 and FADS2) code for enzymes required for synthesis of omega-3 and omega-6 long-chain polyunsaturated fatty acids (LCPUFA) important in the central nervous system, inflammatory response, and cardiovascular health. SNPs in these genes are associated with numerous...

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Detalhes bibliográficos
Main Authors: Reardon, Holly T., Zhang, Jimmy, Kothapalli, Kumar S.D., Kim, Andrea J., Park, Woo Jung, Brenna, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404253/
https://ncbi.nlm.nih.gov/pubmed/22748975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2012.04.011
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