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c-Myb interacts with the glucocorticoid receptor and regulates its level in pre-B-acute lymphoblastic leukemia cells()

Glucocorticoid (GC) hormones are used in the treatment of hematopoietic malignancies. When the GC binds to the glucocorticoid receptor (GR) protein, c-Myb and GR are recruited at the Glucocorticoid Response Unit in the DNA. Here we demonstrate that c-Myb interacts with the GR and that decreasing c-M...

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Detalhes bibliográficos
Main Authors: Sarvaiya, Purvaba J., Schwartz, Jason R., Geng, Chuan-dong, Vedeckis, Wayne V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404235/
https://ncbi.nlm.nih.gov/pubmed/22516378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.03.024
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