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A Multi-Factorial Genetic Model for Prognostic Assessment of High Risk Melanoma Patients Receiving Adjuvant Interferon

PURPOSE: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of patients experience side effects and toxicity which outweigh the benefits. The current study attempts to...

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Detalhes bibliográficos
Main Authors: Wang, Ena, Zhao, Yingdong, Monaco, Alessandro, Uccellini, Lorenzo, Kirkwood, John M., Spyropoulou-Vlachou, Maria, Panelli, Monica C., Marincola, Francesco M., Gogas, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404079/
https://ncbi.nlm.nih.gov/pubmed/22911710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040805
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