A New Mathematical Model for the Interpretation of Translational Research Evaluating Six CTLA-4 Polymorphisms in High-Risk Melanoma Patients Receiving Adjuvant Interferon

Adjuvant therapy of stage IIB/III melanoma with interferon reduces relapse and mortality by up to 33% but is accompanied by toxicity-related complications. Polymorphisms of the CTLA-4 gene associated with autoimmune diseases could help in identifying interferon treatment benefits. We previously geno...

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Główni autorzy: Pancoska, Petr, Kirkwood, John M., Bouros, Spyros, Spyropoulou-Vlachou, Maria, Pectasides, Eirini, Tsoutsos, Dimosthenis, Polyzos, Aristidis, Markopoulos, Christos, Panagiotou, Petros, Castana, Ourania, Bafaloukos, Dimitrios, Fountzilas, George, Gogas, Helen
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2014
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3903519/
https://ncbi.nlm.nih.gov/pubmed/24475110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086375
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