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Fast and Non-Toxic In Situ Hybridization without Blocking of Repetitive Sequences

Formamide is the preferred solvent to lower the melting point and annealing temperature of nucleic acid strands in in situ hybridization (ISH). A key benefit of formamide is better preservation of morphology due to a lower incubation temperature. However, in fluorescence in situ hybridization (FISH)...

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Sonraí Bibleagrafaíochta
Main Authors: Matthiesen, Steen H., Hansen, Charles M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404051/
https://ncbi.nlm.nih.gov/pubmed/22911704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040675
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