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COP9 Signalosome Component JAB1/CSN5 Is Necessary for T Cell Signaling through LFA-1 and HIV-1 Replication

To determine critical host factors involved in HIV-1 replication, a dominant effector genetics approach was developed to reveal signaling pathways on which HIV-1 depends for replication. A large library of short peptide aptamers was expressed via retroviral delivery in T cells. Peptides that interfe...

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Detalhes bibliográficos
Main Authors: Kinoshita, Shigemi M., Krutzik, Peter O., Nolan, Garry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404009/
https://ncbi.nlm.nih.gov/pubmed/22911848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041725
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