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Equine estrogens differentially inhibit DNA fragmentation induced by glutamate in neuronal cells by modulation of regulatory proteins involved in programmed cell death

BACKGROUND: Recent data indicate that excitotoxicity of high levels of neurotransmitter glutamate may be mediated via programmed cell death (apoptosis) and that it can be prevented in HT22 mouse hippocampal cells by various equine estrogens with Δ(8),17β-estradiol (Δ(8),17β-E(2)) being the most pote...

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Detalhes bibliográficos
Main Authors: Zhang, YueMei, Lu, XiaoFeng, Bhavnani, Bhagu R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC340384/
https://ncbi.nlm.nih.gov/pubmed/14693041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-4-32
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