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An analog of the natural steroidal alkaloid Cortistatin A potently suppresses Tat dependent HIV transcription
The human immunodeficiency virus type I (HIV) Tat protein, a potent activator of HIV gene expression, is essential for integrated viral genome expression and represents a potential antiviral target. Tat binds the 5′ terminal region of HIV mRNA’s stem-bulge-loop structure, the Trans-activation Respon...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403716/ https://ncbi.nlm.nih.gov/pubmed/22817991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.016 |
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