Structural and enzymatic characterization of BacD, an l-amino acid dipeptide ligase from Bacillus subtilis

BacD is an ATP-dependent dipeptide ligase responsible for the biosynthesis of l-alanyl-l-anticapsin, a precursor of an antibiotic produced by Bacillus spp. In contrast to the well-studied and phylogenetically related d-alanine: d-alanine ligase (Ddl), BacD synthesizes dipeptides using l-amino acids...

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Main Authors: Shomura, Yasuhito, Hinokuchi, Emi, Ikeda, Hajime, Senoo, Akihiro, Takahashi, Yuichi, Saito, Jun-ichi, Komori, Hirofumi, Shibata, Naoki, Yonetani, Yoshiyuki, Higuchi, Yoshiki
Format: Artigo
Sprog:Inglês
Udgivet: Wiley Subscription Services, Inc., A Wiley Company 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403468/
https://ncbi.nlm.nih.gov/pubmed/22407814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2058
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