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Protein hydrogen exchange: Testing current models

To investigate the determinants of protein hydrogen exchange (HX), HX rates of most of the backbone amide hydrogens of Staphylococcal nuclease were measured by NMR methods. A modified analysis was used to improve accuracy for the faster hydrogens. HX rates of both near surface and well buried hydrog...

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Detalhes bibliográficos
Main Authors: Skinner, John J, Lim, Woon K, Bédard, Sabrina, Black, Ben E, Englander, S Walter
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403436/
https://ncbi.nlm.nih.gov/pubmed/22544567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2082
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