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Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs

To investigate the bioequivalence and the population pharmacokinetics of cefuroxime lysine and cefuroxime sodium in healthy beagle dogs. A randomized 2-period crossover design in 18 healthy beagle dogs after receiving 20, 40, and 80 mg/kg of cefuroxime lysine or cefuroxime sodium was conducted. A 3-...

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Detalhes bibliográficos
Main Authors: Zhao, Longshan, Li, Qing, Li, Xingang, Yin, Ran, Chen, Xiaohui, Geng, Lulu, Bi, Kaishun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403372/
https://ncbi.nlm.nih.gov/pubmed/22911056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/507294
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