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The small Rho GTPase Cdc42 regulates neutrophil polarity via CD11b integrin signaling
Neutrophil migration to sites of infection is the first line of cellular defense. A key event of migration is the maintenance of a polarized morphology, which is characterized by a single leading edge of filamentous actin and a contractile uropod devoid of filamentous actin protrusions. Using a mous...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3403354/ https://ncbi.nlm.nih.gov/pubmed/19752396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-195164 |
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