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New Insights into p53 Signaling and Cancer Cell Response to DNA Damage: Implications for Cancer Therapy

Activation of the p53 signaling pathway by DNA-damaging agents was originally proposed to result either in cell cycle checkpoint activation to promote survival or in apoptotic cell death. This model provided the impetus for numerous studies focusing on the development of p53-based cancer therapies....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mirzayans, Razmik, Andrais, Bonnie, Scott, April, Murray, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403320/
https://ncbi.nlm.nih.gov/pubmed/22911014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/170325
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