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Cellular Responses to Platinum-Based Anticancer Drugs and UVC: Role of p53 and Implications for Cancer Therapy

Chemotherapy is intended to induce cancer cell death through apoptosis and other avenues. Unfortunately, as discussed in this article, moderate doses of genotoxic drugs such as cisplatin typical of those achieved in the clinic often invoke a cytostatic/dormancy rather than cytotoxic/apoptosis respon...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Murray, David, Mirzayans, Razmik
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461110/
https://ncbi.nlm.nih.gov/pubmed/32796711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165766
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